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Functional Neurology and PANS/PANDAS

  • Joseph Coppus
  • Jun 22
  • 5 min read

PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) and PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections) are conditions believed to stem from an autoimmune response that disrupts normal brain function, particularly in regions governing behavior, emotion, and movement. In these cases, an infection, most commonly streptococcal bacteria in PANDAS, triggers the immune system to mistakenly target neuronal tissue, especially within the basal ganglia. This immune-mediated inflammation can alter neurotransmitter signaling and disrupt neural circuits, leading to the sudden onset of symptoms like obsessive-compulsive behaviors, motor tics, anxiety, and cognitive disturbances. Understanding the neurophysiology of PANS/PANDAS highlights the complex interplay between the immune system and the brain, and it opens the door to targeted therapies aimed at reducing neuroinflammation and restoring neurologic balance.


Understanding PANS and PANDAS


PANS and PANDAS primarily affect children, marked by sudden shifts in behavior and motor skills. PANDAS is specifically triggered by streptococcal infections. This leads to the immediate onset of obsessive-compulsive thoughts and involuntary movements, transforming everyday life for children and their families. Research indicates that nearly 1 in 200 chil

dren diagnosed with a strep infection may subsequently develop PANDAS symptoms. However, we have found in our clinical practice that there are many things other than strep that can lead to the presentation of PANDAS.


Conversely, PANS encompasses a wider range of potential triggers, such as other infections or autoimmune conditions. The hallmark of both ailments is their abrupt onset. Children may exhibit symptoms like tremors, motor tics, and psychiatric disturbances. Understanding these conditions is essential for developing effective treatment options.




The Role of Functional Neurology


Functional neurology is a growing field that centers on the brain's capacity to change and adapt through neuroplasticity. This adaptability is particularly important for those with movement disorders. Functional neurologists focus on assessing a child's cognitive, emotional, and motor systems to formulate a comprehensive treatment strategy, aiming to tackle both symptoms and root causes associated with PANS and PANDAS.


Through specialized therapies and exercises, the objective is to forge stronger neural connections, empowering children to regain voluntary movement and diminish tics and tremors. For example, a child struggling with tics may engage in specific activities that promote awareness and control over their movements.


Functional neurology offers a targeted, non-pharmaceutical approach to addressing the neurophysiological imbalances seen in PANS/PANDAS by focusing on restoring healthy brain function and modulating neuroinflammation. Through detailed neurological assessments, practitioners identify areas of disrupted neural activity, often within the basal ganglia, cerebellum, and prefrontal cortex, and apply individualized therapies such as sensory-motor integration, vestibular stimulation, neurofeedback, and nutritional support to promote neuroplasticity and calm the overactive immune-brain response. By improving the function of different brain regions, functional neurology can help reduce symptoms like tics, OCD behaviors, anxiety, and emotional dysregulation, offering a valuable adjunct to medical and immunological treatments.


How Neuroplasticity Works


Neuroplasticity refers to the brain’s extraordinary ability to reorganize itself by forming new neural pathways. This ability is crucial in the recovery process for movement disorders.


Through tailored therapeutic activities, such as rhythm-based tasks, cognitive exercises, and sensory integration techniques, children can fortify existing neural connections and even foster new ones. In fact, studies have shown that simple repetitive movements can enhance brain function and lead to improvements in motor control and emotional well-being. Children involved in these therapies often report better regulation of their actions and feelings, translating into a significantly improved quality of life.


Treatment Approaches in Functional Neurology


Functional neurology offers diverse treatment methods customized to each child's needs. Key strategies include:


1. Neurofeedback


Neurofeedback is a technique where children learn to modify their brain wave activity. Research indicates this approach can enhance self-regulation of motor functions, making it an effective tool for tackling tics and compulsive behaviors associated with PANS and PANDAS. A study showed that participants experienced a 30% reduction in tics after undergoing neurofeedback sessions.


2. Customized NeuroRehab Programs


A customized neurorehabilitation plan is essential in the care of children with PANS/PANDAS, as no two brains or immune responses are the same. Tailoring care based on a child’s unique neurological findings allows for more precise and effective interventions, targeting specific areas of dysfunction rather than using a one-size-fits-all approach. By combining clinical findings with functional testing, a personalized plan can include a combination of sensory-motor exercises, vestibular rehab, cognitive training, and dietary support to help retrain the brain and support long-term recovery. This individualized strategy not only promotes better outcomes but also empowers families with a clear, step-by-step roadmap for healing.


The Importance of Early Intervention


Seeking timely diagnosis and treatment for PANS and PANDAS is vital to enhancing outcomes. If sudden behavioral or motor changes are observed, it is imperative for caregivers to consult a healthcare professional. Starting functional neurology interventions early can optimize a patient's outcomes. The combination of prompt intervention and targeted therapies sets the stage for a higher chance of recovery.


Family Support and Education


Living with movement disorders such as PANS and PANDAS can be overwhelming. Education and support play crucial roles in the recovery journey. Families should explore community resources or support groups, which can provide shared experiences and effective coping strategies. Understanding PANS and PANDAS also fosters a productive partnership with healthcare providers, improving the overall treatment experience for everyone involved.


Real-Life Impact: Success Stories


As a functional neurologist, I’ve had the privilege of working with several children diagnosed with PANS who have experienced marked recovery through individualized neurorehabilitation. By addressing the underlying neurological dysfunction and calming the brain’s inflammatory response, I’ve seen significant improvements in symptoms such as motor tics, OCD behaviors, anxiety, and emotional dysregulation. These outcomes weren’t the result of a single intervention, but rather a carefully crafted, patient-specific plan that integrated brain-based therapies, nutritional strategies, and autonomic regulation. It’s been incredibly rewarding to witness these children regain function, confidence, and quality of life as their brains begin to heal.


The Path Forward


As research into movement disorders, particularly PANS and PANDAS, advances, our understanding continues to evolve. The focus on functional neurology and neuroplasticity offers new hope in treatment, showcasing the brain's incredible healing potential.


By staying informed and proactive about comprehensive treatment options, families can strive for the best possible outcomes for their children.


Final Thoughts


The realm of movement disorders, especially PANS and PANDAS, poses various challenges and uncertainties. Nevertheless, through the innovative methods of functional neurology that tap into the brain's adaptability, recovery is achievable and realistic.


If your child is struggling with sudden changes in behavior, motor function, or emotional regulation, and you suspect PANS or PANDAS may be the cause, don’t wait for symptoms to worsen. Early intervention can make a profound difference. At Delta Neuro Health, we specialize in identifying and treating the underlying neurological imbalances that drive these complex conditions. Schedule a consultation today to begin a personalized path toward healing and give your child the support their brain needs to thrive.



Call: (614) 706-2093



A smiling child engaged in a therapy session, showing signs of progress and comfort during treatment for PANS, highlighting hope and healing through neurorehabilitation.

 
 
 

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